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To: VxH
No. Chimerism occurs when two normal embryos fuse or when cells from one normal embryo are transferred to the twin embryo. This is a normal occurrance--in fact, mothers who have born a baby boy have a handful of XY cells from their baby scattered through their tissues. It is a testimony to the plasticity of stem cells.

There is a vast difference between proposing a hypothesis and jumping to a conclusion. You have nothing (and there is nothing) to support your position that there is a genetic bias towards chimerism, yet you're putting forth some sort of eugenic program in spite of your ignorance. Not very impressive.

79 posted on 02/27/2004 5:04:00 PM PST by ahayes
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To: ahayes
>>This is a normal occurrance--in fact, mothers
>>who have born a baby boy have a handful of XY cells
>>from their baby scattered through their tissues

How does the mother's immune system know not to reject the cells?

Genetics.
80 posted on 02/27/2004 6:49:22 PM PST by VxH (This species has amused itself to death.)
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To: ahayes
>> You have nothing (and there is nothing) to support your position that there is a genetic bias towards chimerism
 
Really? 
Another possibility for the coexistence of the XX males and true hermaphrodites within the same family may be explained on the basis of inheritance of genes that predispose to chimerism. Many cases of sporadic true hermaphroditism have been shown to be on the basis of chimerism of 46,XX and 46,XY zygotes. In one pedigree, a mosaic 46,XX/XY hermaphrodite had a 46,XX brother (pedigree 2–15) (48). The proportion of 46,XY-bearing cells in the gonad may have been so great that the gonad of the 46,XX male was a testis. Gonadal mosaicism can be implied for the pedigree where two brothers are 46,XX true hermaphrodites with male phenotype, one carrying a paternally transmitted marker, possibly of Y chromosomal origin and the other not (pedigree 2–16) (49).
 
http://jcem.endojournals.org/cgi/content/full/85/2/483
 
 

81 posted on 02/27/2004 6:57:11 PM PST by VxH (This species has amused itself to death.)
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