[HiTech RedNeck]

However, IBO also produced neurodegeneration of Purkinje cells and gliosis of Bergmann astrocytes in the cerebella of rats given even a single dose (100 mg/kg, i.p.).

That would be a lot of ibogaine if scaled up to the size of a man -- 10 grams or more.

[neverdem]

That would be a lot of ibogaine if scaled up to the size of a man -- 10 grams or more.

True for a man at least weighing more than 220.0 pounds. The proverbial average "person" is 70 kilograms, i.e. 154 lb IIRC, although that was before the epidemic of obesity.

[neverdem]

Pardon my error, that's 220.4 lb, IIRC.