Actually, they wouldn't want to cut Canada off. 1000% is still a darn good profit. Not what they get here, but still pretty good.
If you had a product that you could sell for a 50x markup in one part of the world, i'm sure you'd still be willing to sell it to anyone who would but it for a 10x markup in another part.
1000% is still better than the profit margin on most other products on the market. (Heck, automobiles have only a 5-10% markup). Drugs are among the most profitable commodities on the face of the planet.