Certainly possible, and hackers can never be underestimated (can't say that enough), but a single serverhost attack is never going to infect millions of systems, not unless it was hosted overseas at a server farm or something, but then you have latency issues and the ability to block the requests at the major ISPs. However those sorts of attacks could be the next wave, as these anti-American hackers are relentless in their pursuit of causing us harm.
a single serverhost attack is never going to infect millions of systems