To the contrary, I'd expect more of the "It's really a religion of Peace" crap from the politicians. Would you REALLY expect awe-inspiring massive retaliation? Or more political tapdancing while seeking specific targets?
Suppose the Black Cube in Mecca were vaporized in retaliation? Wouldn't that just maybe get the Moos to ponder whether God's really on their side? But it wouldn't ever happen.