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To: NYer
Hmmm..... is this proven, or just a theory? I mean, did they actually take DNA samples from different parts of this woman and find two different sets of DNA? Cause otherwise, the babies-switched-at-the-hospital suggestion seems far more plausible.
10 posted on 11/17/2003 10:28:21 AM PST by wizardoz
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To: wizardoz
Yes, and yes. This woman has cells with one specific 46 chromosome identity and living right alongside those cells, cells with a different 46 chromosome complement. What makews this possible, as I understand it, is that both sets of cells have the same histocompatibility thus are both recognized as being 'her'. [This is a function of same mitochondrial make up, since both sets of chromosomes derived from oocytes produced by her mother's body; mitochondria is passed down to each of us through the mother's gamete(s).]
20 posted on 11/17/2003 10:35:45 AM PST by MHGinTN (If you can read this, you've had life support from someone. Promote life support for others.)
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To: wizardoz
I have to chime in again because I have given incorrect directions.

The mitochondria of the two early embryos may have mixed around time of both embryos 'hatching' from the zona pellucida in which they transited to the uterus. HOWEVER, the histocompatibility would be directly related to the membrane formation of stem cells subsequent to the welding of the embryos, since it is the molecular identity complex in the cell membrane that mediates the primary histocompatibility and thus tissue rejection. Somehow (and I have no idea how), the susequent cell membrane formation with stem cells, following the welding of the two embryos inside the chamber formed by a single placental organ, resulted in a cellular membrane combining the histocompatiblity molecules and thus commonality was transmitted to every cell that developed into the birthed organism. [Neat trick, don'tcha know. If scientists could figure out how to do it in a lab setting, tissue rejection that plagues organ transplantation would all but vanish!]

76 posted on 11/17/2003 12:19:37 PM PST by MHGinTN (If you can read this, you've had life support from someone. Promote life support for others.)
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