Her best shot is likely a Biden win. It will be even more obvious by that time that Joe’s memory and speech issues are serious, and she can step in as the 2024 Heir Apparent. If the Wuhan Virus isn’t a disaster, Pence will be well positioned to beat whatever candidate the Dems put up, and Michelle balks at even running.
She’ll never win.
She might be running against Sarah Palin if this video is any indication:
https://www.youtube.com/watch?v=zJPcC1-uAeM&feature=emb_logo