“The Panel’s recommendation is primarily informed by adequately powered, randomized trials of ivermectin that reported clinical outcomes. Studies that randomized participants to ivermectin or a matched placebo had the greatest impact on the Panel’s recommendation.6-13
Trials have failed to find a clinical benefit from the use of ivermectin for the treatment of COVID-19 in outpatients.”
https://www.covid19treatmentguidelines.nih.gov/therapies/miscellaneous-drugs/ivermectin/
Ivermectin was supposed to be coupled with Zinc as a catalyst for making the zinc better absorbed and more effective. Quercetin was an alternative to the ivermectin that was promoted.