Like Lucifer, when humans discovered their minds can invent (even in error), anything they want, they very arrogantly came to think they could re-invent their biological selves, to anything they “desire”, even contrary to their own personal biology. Maybe Lucifer has had a hand in human’s coming to that belief, he surely thought he could betray his own creation by his creator, and by that betrayal lost G-d’s approval forever.
I blame Plato...