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Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis
American Heart Association Journals ^ | January 4th, 2023 | Lael M. Yonker, Zoe Swank, et al

Posted on 01/10/2023 6:00:46 PM PST by shadowlands1960

Abstract BACKGROUND: Cases of adolescents and young adults developing myocarditis after vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted mRNA vaccines have been reported globally, but the underlying immunoprofiles of these individuals have not been described in detail.

METHODS: From January 2021 through February 2022, we prospectively collected blood from 16 patients who were hospitalized at Massachusetts General for Children or Boston Children’s Hospital for myocarditis, presenting with chest pain with elevated cardiac troponin T after SARS-CoV-2 vaccination. We performed extensive antibody profiling, including tests for SARS-CoV-2–specific humoral responses and assessment for autoantibodies or antibodies against the human-relevant virome, SARS-CoV-2–specific T-cell analysis, and cytokine and SARS-CoV-2 antigen profiling. Results were compared with those from 45 healthy, asymptomatic, age-matched vaccinated control subjects.

RESULTS: Extensive antibody profiling and T-cell responses in the individuals who developed postvaccine myocarditis were essentially indistinguishable from those of vaccinated control subjects, despite a modest increase in cytokine production. A notable finding was that markedly elevated levels of full-length spike protein (33.9±22.4 pg/mL), unbound by antibodies, were detected in the plasma of individuals with postvaccine myocarditis, whereas no free spike was detected in asymptomatic vaccinated control subjects (unpaired t test; P<0.0001).

CONCLUSIONS: Immunoprofiling of vaccinated adolescents and young adults revealed that the mRNA vaccine–induced immune responses did not differ between individuals who developed myocarditis and individuals who did not. However, free spike antigen was detected in the blood of adolescents and young adults who developed post-mRNA vaccine myocarditis, advancing insight into its potential underlying cause.

(Excerpt) Read more at ahajournals.org ...


TOPICS: Health/Medicine; Science
KEYWORDS: bnt162b2; covid19; myocarditis; vaccination
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1 posted on 01/10/2023 6:00:46 PM PST by shadowlands1960
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To: shadowlands1960

Does anyone know if dialysis would clear the blood of this stuff?


2 posted on 01/10/2023 6:03:04 PM PST by ryderann
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To: ryderann

good question...


3 posted on 01/10/2023 6:04:35 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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To: shadowlands1960

bookmark.


4 posted on 01/10/2023 6:08:45 PM PST by dadfly ( )
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To: ryderann

Spike proteins are twisted protein pieces basically like prions. You can’t get rid of this stuff through dialysis.


5 posted on 01/10/2023 6:11:47 PM PST by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
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To: Secret Agent Man
You can’t get rid of this stuff through dialysis.

Especially if your cells are still manufacturing it, contrary to the claims that it would only do so for a limited time after “vaccination.”

6 posted on 01/10/2023 6:19:23 PM PST by noiseman (The only thing necessary for the triumph of evil is for good men to do nothing.)
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To: Secret Agent Man

A person posting on another thread tonight blamed it on clinical technique... clinicians not aspirating for blood before injects... so vaccine in some cases will go direct into bloodstream... I wonder if that would account for why this strikes some and leaves other’s unharmed?


7 posted on 01/10/2023 6:20:20 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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To: shadowlands1960

“free spike antigen was detected in the blood of adolescents and young adults who developed post-mRNA vaccine myocarditis, advancing insight into its potential underlying cause”

What does that mean?


8 posted on 01/10/2023 6:21:38 PM PST by BenLurkin (The above is not a statement of fact. It is either opinion, or satire, or both.)
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To: BenLurkin

Apparently those free spikes were only found in young people who had developed myocarditis... so they are hopeful this will lead them to the etiology of these events.


9 posted on 01/10/2023 6:23:24 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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To: ryderann

They can replace the standard dialysis filters with one that can trap cytokines, for example, so it may be possible. ...Although the procedure of dialysis carries an increased risk of infection and other risks so you might not want to do that. Better to try some other intervention that reduces the mischief the spike proteins are causing.


10 posted on 01/10/2023 6:26:32 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: shadowlands1960

etiology

I’m guessing that doesn’t mean where they had lunch.


11 posted on 01/10/2023 6:26:33 PM PST by BenLurkin (The above is not a statement of fact. It is either opinion, or satire, or both.)
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To: shadowlands1960

They should also have assayed for continued presence of the mRNA.

Btw, the journal is Circulation. A good journal.


12 posted on 01/10/2023 6:28:51 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: steve86

What about blood that’s been donated for transfusions. Can it be put through that process?


13 posted on 01/10/2023 6:30:31 PM PST by ryderann
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To: ryderann

“ Does anyone know if dialysis would clear the blood of this stuff?”

Unlikely.

The protein is made the the mRNA which is probably retained in cells.

But, you never know until done.


14 posted on 01/10/2023 6:30:36 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: ifinnegan
They should also have assayed for continued presence of the mRNA. Btw, the journal is Circulation. A good journal

Thanks.. I'll remember if I post anything from them again. They may have, I only read the summary...
15 posted on 01/10/2023 6:32:01 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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To: BenLurkin

I should have said ‘those reactions to free spikes’ as it was antigen they discovered in the cases with myocarditis..


16 posted on 01/10/2023 6:37:10 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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To: ryderann

Donated blood could be and is filtered, of course, but I am not knowledgeable as to whether the required filter characteristics are feasible. Sometimes what you can do in a lab is not easily transferred to production systems, due to economics or other reasons.


17 posted on 01/10/2023 6:44:06 PM PST by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: shadowlands1960

5mi from here

Schuyler County Teen Recovering From Stroke; GoFundMe Page Established

Keyonna Garrison is a junior at Odessa-Montour High School and is starting goalie on the school’s soccer team. According to her family, Garrison’s stroke resulted from issues with her vertebral artery. The 16-year-old was initially treated at Corning Hospital before being transferred to the Intensive Care Unit at Strong in Rochester


18 posted on 01/10/2023 6:57:30 PM PST by Chode (there is no fall back position, there's no rally point, there is no LZ... we're on our own. #FJB)
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To: steve86

Thank you.


19 posted on 01/10/2023 6:59:05 PM PST by ryderann
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To: Chode

I follow my local FB scanner page. They are all the time getting calls to middle and HS for kids having seizures... people say it’s normal... I don’t remember it being ‘normal’ when I was in school.


20 posted on 01/10/2023 7:00:59 PM PST by shadowlands1960 (We live in a world of intolerance masked as tolerance. RUSH LIMBAUGH)
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