Here he is talking about his role in repurposed drugs for Zika:
https://www.contagionlive.com/view/repurposing-licensed-drugs-for-use-against-the-zika-virus
I find the notion interesting and nothing in the article you referenced alarming per se. Indeed, the off-label uses of medications -- especially the inexpensive ones -- seems an avenue worth pursuing, or resisting depending on your place in the business "battle."
The seemingly controversies over ivermectin and hydoxychloroquine are of the same ilk, in which bureaucracies allow/disallow off-label or repurposed uses. Malone seems to be for repurposing ivermectin for prophylaxis and eearly treatment, and therefore at odds with the NIH/CDC/FDA.
I cam up empty as regards your citing of Malone's role in "repurposing" remdesivir, though Fauci and his aggressive marketing of the drug is easily found, with that "gold standard" nonsense for a short term (and failed) study which cause remdesivir to be placed atop the "hospital protocol."
If you've other sources/citations, it would be appreciated seeing them.