“Why ADE Hasn’t Been a Problem With COVID Vaccines
— Even with new variants, it’s unlikely antibody-dependent enhancement will be an issue”
https://www.medpagetoday.com/special-reports/exclusives/91648
Newer Vaccines Are Safer
Despite hesitancy about the relative newness of mRNA and adenoviral vector vaccines, these vaccines, in fact, have better safety profiles in terms of ADE than older types of vaccines, according to Bloom.
“The bottom line is that not only is the new technology faster to respond to a new viral pandemic, but so much safer and much more clearly scientifically designed,” he said. “The S protein vaccines are so much cleaner, so much more carefully defined, and so much lower risk. All you’re seeing is one protein from that virus. So the chances for ADE are much slimmer than with any of the older ways for making virus vaccines.”
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