Yes, of course. There is no data to suggest otherwise.
140 million people in the US have gotten a COVID-19 vaccine. COVID-19 has a 0.65% infection fatality rate (https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scenarios-archive/planning-scenarios-2020-09-10.pdf). If that same 140 million people had COVID-19 instead of the vaccines, roughly 910,000 of them would be dead. That’s pretty simple math.
Israel is about 1-2 months ahead of the US in terms of how much of the population has been vaccinated. Their average daily new COVID-19 cases have dropped from nearly 10,000 per day to 140 per day. Their average daily new deaths from COVID-19 has dropped from nearly 100 per day to 3. 3 deaths in the entire country. And their lives have largely returned to 2019-style normal (https://www.washingtonpost.com/world/middle_east/israel-coronavirus-vaccine-herd-immunity/2021/04/20/e4e1199c-a118-11eb-b314-2e993bd83e31_story.html). Israel is primarily using the Pfizer vaccine, which was developed and tested in the United States. The US solution to a Chinese problem.
Data coming out of Israel has demonstrated that the vaccine blocks 94% of asymptomatic infections and 97% of symptomatic infections (https://www.cnbc.com/2021/03/11/pfizer-covid-vaccine-blocks-94percent-of-asymptomatic-infections-and-97percent-of-symptomatic-cases-in-israeli-study.html). They’ve observed minimal side effects, as have we.
So yes, all the data collected thus far after a billion people around the world have been vaccinated is that the vaccines available in the US are both safe and effective.