In 1869, Remington actually introduced a .46 caliber handgun with their cartridge conversion of the New Army Model of 1863 cap and ball revolver. Although Smith & Wesson had been making .22 and .32 caliber cartridge revolvers for over a decade, Remington's was the very first large caliber revolver on the market. Colt didn't introduce one until 1872.
Wow. Learn somthin’ new everyday. Thanks.