How does (or not) the immuno effects of psoriasis relate to susceptibility to the pulmonary effects of corona virus?
He would have had clinically significant pre-existing inflammation from an auto-immune disorder. Add to that the added burden of the virus and he probably entered into a cytokine storm with his lungs filling with fluid.
“How does (or not) the immuno effects of psoriasis relate to susceptibility to the pulmonary effects of corona virus?”
Psoriasis is immunodysregulatory. It isn’t thought to be immunosuppressive. In fact, untreated psoriasis is thought to bolster immunity. Most effective treatments for psoriasis ARE immunosuppresive, by design. There are many current therapies, both old drugs and very modern injectable biologics. Therefore, the question remains if this boy was receiving an immunosuppressive medication for psoriasis that made him more vulnerable to the coronavirus infection and its ill-effects.
Psoriasis is caused by an immune system having an overreaction. The same kind of overreaction can happen in your lungs as a reaction to the virus.
Conversely psoriasis ointment lowers the reactions of your immune system, at least in the areas that you apply it.
I would think either way could cause a problem.