Never underestimate the 22lr. Read about the battle of Grozny in the 90’s. Chechen snipers raised bloody hell with Russian troops forcing them out using 22lr at close range and head shots. A bloody urban slugfest.
Forced the Russians back who then resorted to their tried and true prepping with heavy artillery, air strikes and tanks against guys who had initially had .22’s and now had up gunned to heavier Russian ordinance lifted from the dead enemy.
Absolutely. Had a good friend who used to take deer as broke kid in Illinois with a bolt action .22lr. He said all you have to do is be patient and hit them in the eye. The .22 also has a nasty way of bouncing around in the body and tearing stuff up.