Shooting one of those are not on my bucket list, at a minimum keep your wrists straight.
It could very well be the final item on your bucket list.
I shot a .460 once, do not want to again.
Even with two hands, locked wrists and elbows it carried the gun up over my head
I shot a couple cylinders in a five and “Extreme stubby”. The latter was the least uncomfortable. The shock waves were so intense that my sinuses ached and needed compresses. The owner mixed the loads with a few fired cartridges and a couple of the 700 grainers. I’m glad I sold my unfired long barrel version as shooting these guns is not enjoyable. I did buy a few hundred bullets to shoot low-velocity loads for fun. Will shoot those bullets in black powder rifles. Be forwarned that double ear protection recommended.
I have the same handgun and the same ammo for bear protection here in Alaska. I don’t go out and practice shoot with those babies! If you don’t break down you’re not going to stop them!