Exactly. My wife is a retired nurse practitioner. She has commented on the same characteristics. People who drink alcohol in excess and smoke or do drugs, do not grow old gracefully. Heavy wrinkles are one of the first signs.
In particular, there are 2 sisters I know where the younger, by 6 years, was/is a heavy drinker and smoker and looked AT LEAST 10 years older than her older sister, by the time she was 40.
I have seen this most notably in women, simply because I work in construction, where weather and working conditions can take their toll and women, working in offices, have skin similar to hard drinking and or smoking men in construction.
There is also a woman I have worked with in the trades, who I met when we were both in our 20's. Back in the day she was QUITE ATTRACTIVE ...
ESPECIALLY for being in the trades.
Today, though you can catch glimpses of her former attractiveness, she looks like she's in her late 50's, and a hard late 50's at that. Despite the fact she is mid to late 40's and was out of the trades for about a dozen years raising kids. She is constantly smoking on the job, when ever possible. Noticeably so.
Then of course I see it in men in the trades. Blue collar workers have a higher percentage of smokers than white collar. Also more drinkers. Drinkers with disposable income, who can drink away $100-$200+ EVERY week.