I read an account of a Canadian Indian woman picking blackberries who killed a large grizzly with a .22lr single shot. When she saw the grizzly coming for her she three herself in the middle of the large thorny blackberry bushes hoping the bear wouldn’t try to get in the thorns himself to get her. He did and she fired one shot at point blank range.
It does have a lot of penetration close up.
*threw herself
I think I read about that too but I have a .22 mag semi auto and I sure would hate for that to be my line in the sand with even a black bear. LOL!
.22 rifle used to kill world record grizzly:
http://gunwatch.blogspot.com/2014/11/what-22-rifle-did-bella-twin-use-to.html