Tell that to a Randian.
It is only an ultimate goal, and end in itself, that makes the existence of values possible. Metaphysically, life is the only phenomenon that is an end in itself: a value gained and kept by a constant process of action. Epistemologically, the concept of “value” is genetically dependent upon and derived from the antecedent concept of “life.” To speak of “value” as apart from “life” is worse than a contradiction in terms. “It is only the concept of ‘Life’ that makes the concept of ‘Value’ possible.” In answer to those philosophers who claim that no relation can be established between ultimate ends or values and the facts of reality, let me stress that the fact that living entities exist and function necessitates the existence of values and of an ultimate value which for any given living entity is its own life. Thus the validation of value judgments is to be achieved by reference to the facts of reality. The fact that a living entity is, determines what it ought to do. So much for the issue of the relation between “is” and “ought.”
Scientology manages to.
You can argue how well (and I’d be right there with you) but the entire system of ethics they use is based of the 8 dynamics, the urges to survival on 8 levels, self, family, groups, species, living things, physical objects, spiritual things and “everything else” (or God).
If is and ought are perceived in ignorance then, no, we cannot deduce what ought to be from what is. We have at our disposal, however, Notes from the Author, who Himself exists outside of science.