Now they are using an S21 variant with nuclear warheads - sort of a broad spectrum spray. They are more than able to take out any ICBM, MIRVed or not. We are that far behind.
We, on the other hand, were trying to effect a direct hit on incoming missiles, a proposition not solved until lately, and only good against a few missile warheads at a time - a proposition the Russians never considered.
Then again in the 50s and 60s, Russian workers wearing their white paper overalls used to handle refined plutonium with their bare hands, so they willing to accept a bit of radiation to save the Motherland ... and, not to put too fine a point on it, those that survived said they would do it again.