PX4s are too new and have yet to stand the test of time.
A good friend had to return a .40 cal PX4 because of wicked trigger snap. It was a Model C DAO with the cut down hammer. It was really a bad design.
He also had to repair a .40 cal CX 4 that came with a defective mag retention spring.
He has never had any issue with Glocks.
I own and love a PX4 Storm in .40. Type F, I’ve not had the difficulties that Gabrial mentioned. Mine’s the full-size. I have a friend who swears by his compact as well.
The ergo design is simply amazing. I can reach the clip release, slide catch, AND the safety/decocker with my thumb - all without taking the sights off the target.
But I agree, this all comes down to personal feel and preference. The first time I ever held this particular firearm, it was home in my hands.