Prohibition CREATED the mob. THAT genie wasn’t ever going to be put back in the bottle.
No it didn't.
The mob (in the sense of ethnically-based organized crime operations) was well-established by the 1820s in the US.
There were mob wars in New Orleans and New York by the middle of the nineteenth century.
The mob's business model is independent of narcotics, alcohol or any other product.
Its business model is to provide protection for criminal enterprises from other criminal enterprises.
Whether that criminal enterprise is manipulating prices, or gambling, or insurance fraud, or illegal drug trafficking, or prostitution, or smuggling illegals, or fraudulent union contracts, or embezzlement, or prescription drug fraud (an enormous business for the mob today and one that involves completely legal narcotics) it does not matter.
It is a myth that Prohibition "created" the mob. All Prohibition did was make the mob more visible - because average citizens were much more likely to visit a speakeasy in 1925 than they were to steal from cargo vessels or create mail fraud rings.
The Feds became aware in the 1920s of what the police of every major city in the US were well aware of in 1890.