There are actually several different types of Kryptonite.
The most famous, Green Kryptonite, will eventually kill a super Kryptonian (e.g. Superman, Supergirl), but it takes a while, usually long enough for a weakened Superhero to say or do something to prevent his death.
Red Kryptonite causes unpredictable but temporary side effects. It is frequently used by the main stream media, sometimes to their detriment (it could, for instance, make a superhero temporaily insane, or temporarily make him 10 feet tall).
Exposure to Gold Kryptonite will remove super powers permanently. The Macaca guy was found with that. There may have been some in the keel of the S.S. Monkey Business as well.
Blue Kryptonite is used only on Bizarro Kryptonians, and is useful against most Democrats.
I think your cartoon needs a little more development.