The destruction of ground surface targets is straight forward: Initial strikes blind the radar and destroy air defenses, the enemy air power is annihilated and then the ground surface targets can be destroyed at leisure by either pin-point guided munitions or by B-52 carpet bombings. A MOAB would look more impressive but is not really necessary.
The real dilemma in this air campaign will be the feasibility of destroying hardened, deep below-ground facilities with conventional bunker busters.
So you believe multiple stand-off, long distance strikes after first wiping out the Iranian Air Force would be most effective?
That does take a while. It wouldn't be like the Israelis at Osirak.