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To: Ichneumon
"...the total number of injected transduced cells — 92 x 106 and 133 x 106 for patients P4 and P5, respectively..."

So it's not actually "3 of only 9 integrations", as tallhappy falsely claims, since just *two* out of the nine total patients had TWO HUNDRED TWENTY FIVE MILLION retrovirus-treated cells pumped into their bodies...

You are actually funny in your misunderstanding. Retrovirus treated is not necessarily the same as virally integrated, not all integrated will be of relevance in the treatment (analagous to an evolutionary insertion that occurs long term).

After transplanting 100 million vector exposed cells )random exposure) in 11 patients, 9 patients had functional integrations and of the 9 three had integrations at the LMO2 locus

That's very non-random.

Recall as I pointed out that specificity of integration involves the initial molecular events related to the DNA recombination event and subsequent cellular selction processes.

257 posted on 08/24/2005 8:36:58 AM PDT by tallhappy (Juntos Podemos!)
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To: tallhappy

So if I spray an area, blindfolded, with a machine gun, and three people are hit, I can say the bullets were nonrandom because all of the effective bullets hit people.


259 posted on 08/24/2005 8:41:39 AM PDT by js1138 (Science has it all: the fun of being still, paying attention, writing down numbers...)
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