And by "slightly" I mean so slightly as to defy imagination. We are very near "take off" in regard to controlling our own and other genomes. Once that happens, the evidence of a "wild state" will disappear rapidly. I can see folks a thousand years from now debating whether or not there ever were any "wild genomes".
Yup ~ a slightly more advanced civiliation than our own churned it all out in their genome factories.
If the genome were developed by some sort of engineer/scientist, why do some marsupials have egg teeth they never use? Wouldn't it make more sense to not include or to deactivate those genes?
Certainly a competent designer would have done something about the recurrent laryngeal nerve, especially in giraffes.