[robertpaulsen]

"In other words, to make sure that all regulations that it chooses to make will be effective?"

Allow me to rephrase. "Congress shall have the power to regulate commerce among the several states, and shall have the power to make all laws necessary and proper to execute such regulation."

[inquest]

Allow me to rephrase. "Congress shall have the power to regulate commerce among the several states, and shall have the power to make all laws necessary and proper to execute such regulation."

That's more like it. Much more accurate than talking about "effectiveness".