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'Cannabis' acts as antidepressant
BBC ^

Posted on 10/13/2005 9:49:35 PM PDT by traumer

A chemical found in cannabis can act like an antidepressant, researchers have found.

A team from Canada's University of Sasketchewan suggest the compound causes nerve cells to regenerate.

The Journal of Clinical Investigation study showed rats given a cannabinoid were less anxious and less depressed.

But UK experts warned other conflicting research had linked cannabis, and other cannabinoids, to an increased risk of depression and anxiety.

They suggested this could be because different cannabinoids acting at different levels have contradictory effects.

Cannabinoids have been shown to relieve the symptoms of multiple sclerosis and pain relief in humans.

They are naturally present in the body, as well as being found in cannabis.

'Complicated effects'

The Canadian researchers gave rats injections of high levels of one artificial cannabinoid, HU210, for a month.

The animals were seen to have nerve cell regeneration in the hippocampus, which is linked to memory and emotions.

The hippocampus has been shown to generate new nerve cells throughout a person's or an animal's life, but this ability is reduced if cells are engineered to lack a cannabinoid receptor protein called CB-1.

In the Canadian study, rats given the cannabinoid were also found to be less anxious, and more willing to eat food in new environments - a change which would normally frighten them.

However, research has previously linked use of the drug cannabis to long-term damage to mental health, and to increase the risk of mental illness in those who are already genetically susceptible.

In addition, short-term high doses of cannabinoids had also been shown to produce anxiety-like effects in rats and depression-like effects in mice.

But other studies had found that low-doses of cannabinoids helped to reduce anxiety in rodents.

The Canadian team said: "These complicated effects of high and low doses of acute and chronic exposure to cannabinoids may explain the seemingly conflicting results observed in clinical studies regarding the effects of cannabinoid on anxiety and depression."

'Raw cannabis is risky'

Professor Robin Murray, of the Institute of Psychiatry, questioned whether the anti-anxiety and antidepressant effects seen in the animals would be replicated in humans.

He said: "This is a very big leap of faith as they have no data on humans, and the supposed animals' models of anxiety and depression that they use don't have much in common with the human conditions."

Paul Corry, Director of campaigns and communication at Rethink said: "Cannabinoids are an exciting new area for medical research, but it is important to recognise that there are over 60 active ingredients in cannabis - synthetic cannabinoid may be showing evidence of nerve regeneration.

"But as also pointed out in this study, the effects of cannabis on the brain are complex and produce conflicting evidence.

"For most people with severe mental illness, raw cannabis remains a risky substance.

"All medical research needs to be checked before it would make a difference to the hundreds of thousands of people living with severe mental illness in the UK."


TOPICS:
KEYWORDS: anxiety; bongbrigade; burnouts; buttmonkeys; depression; disorders; dopers; druggies; getalifemrleroy; grasssmokahs; potheads; rasta; smoketwojoints; stoners; thatsmrleroytoyou; tuneinturnondropout; wodlist
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To: robertpaulsen
"They ruled that Congress may do so to prevent hindrance to interstate traffic, so a qualified yes."

Ya busted him hard.

221 posted on 10/16/2005 9:48:11 AM PDT by Mojave
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To: Mojave
The word "interstate" doesn't even appear in the Constitution.

You claim there's a difference in meaning between "interstate" and "among the several states"?

If that commerce affects commerce among the states [...], Congress may act.

Where in the Constitution does it say that?

a self-evident truth

A tacit admission on your part that you're begging the question.

Aristotle, call your office.

RP has repeatedly posted cases that precede that court.

Which don't say what he implies they say.

222 posted on 10/16/2005 9:50:45 AM PDT by Know your rights (The modern enlightened liberal doesn't care what you believe as long as you don't really believe it.)
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To: robertpaulsen; Mojave
*yawn* So make that: The Constitution grants Congress the authority to regulate interstate commerce, but not commerce within a single state ... to which the only exception recognized by any Supreme Court before FDR's was to prevent hindrance to interstate traffic.
223 posted on 10/16/2005 9:54:28 AM PDT by Know your rights (The modern enlightened liberal doesn't care what you believe as long as you don't really believe it.)
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To: Know your rights
[If that commerce affects commerce among the states or impedes the ability of Congress to enforce the laws necessary and proper, Congress may act.]

You claim there's a difference in meaning between "interstate" and "among the several states"?

If that commerce affects commerce among the states or impedes the ability of Congress to enforce the laws necessary and proper, Congress may act.

Willful ignorance seems to be your sole defense.

Aristotle, call your office.

His office would tell him that there's someone circulating a poor counterfeit of his thoughts.

Which don't say what he implies they say.

He already quoted you admitting they did.

Tsk.

224 posted on 10/16/2005 9:57:40 AM PDT by Mojave
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To: radioman

methprevention.com is not part of the DEA nor is it part of the meth-is-death. They sell T-Shirts!

Methprevention.com - a division of MMAcreations

"At first glance, we are a talented advertising agency.

You lied and reason.com lied and all lied by taking information off of one site and crediting it to another. Sheesh.


225 posted on 10/16/2005 10:00:42 AM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: Know your rights
prevent hindrance to interstate traffic

The multi-billion dollar illicit fungible drug trade doesn't affect or involve interstate traffic?

You sunk yourself.

I thought you would be weak, but this is just sad.

226 posted on 10/16/2005 10:02:55 AM PDT by Mojave
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To: WildTurkey
methprevention.com is not part of the DEA nor is it part of the meth-is-death.

His source is his keyboard.

227 posted on 10/16/2005 10:04:37 AM PDT by Mojave
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To: radioman
Sorry, I didn't realiize some were incapable of following the links on interlinked websites.

Uh, I think it is you and reason.com that have that problem. You know, attributing data to the DEA that is on some advertising company website.

228 posted on 10/16/2005 10:16:01 AM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: WildTurkey
At first glance, we are a talented advertising agency

ROFL!
Yeah, the Jackson Foundation and MMA are very talented...Maybe that's why they get so many ODCP contracts.

They sell T-Shirts!

They sell the same posters and video as all the other "meth is death" project websites.

Still can't refute the facts?
.
229 posted on 10/16/2005 10:21:36 AM PDT by radioman
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To: radioman
ROFL!

Rolling On Flooring Lying?

230 posted on 10/16/2005 10:23:46 AM PDT by Mojave
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To: Know your rights
"to which the only exception recognized by any Supreme Court before FDR's was to prevent hindrance to interstate traffic."

To which one exception, yes. Not the only.

The USSC did rule in Southern R. CO. v. U.S., 222 U.S. 20 (1911) that required safety devices are not confined to vehicles used in moving interstate traffic, but embrace vehicles used in moving intrastate traffic as well, since there is a substantial relation between the two.

231 posted on 10/16/2005 10:24:32 AM PDT by robertpaulsen
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To: Mojave
Do you think the Wickard substantial effects test is in accordance with the original intent of the Constitution, in your opinion (not the Court's)?
232 posted on 10/16/2005 10:25:47 AM PDT by Ken H
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To: radioman

You have PROVED my point! Here is your post. See how you lie.



"the life expectancy of a habitual meth user is only 5 years." Do the math.


Now here is the NEW site quote that he claims is the source.


The life expectancy of a habitual meth user is as little as 5 years.


See how y'all change the information to make the "math" work. Sheez.


233 posted on 10/16/2005 10:26:26 AM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: radioman
Still can't refute the facts?

Refute this fact. You lied! Your quote that first started all this and was the basis for your 'math'.

"the life expectancy of a habitual meth user is only 5 years." Do the math.

After catching you on 'inserted' data wrongly attributed to the DEA you come up with a new site which has nothing to do with either of the original two sites referenced.

The life expectancy of a habitual meth user is as little as 5 years.

Notice how if you use the actual quote and not your altered quote you can't do the 'math' you cited in your first quote. Thus, you and the other hundreds of websites you refer to are guilty of posting altered content so as to cast doubt on reputable organizations. I believe that would open you up to lawsuits. But y'all are probably well-protected by Soros' legal umbrella.

234 posted on 10/16/2005 10:34:47 AM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: Ken H
Do you think the Wickard substantial effects test is in accordance with the original intent of the Constitution, in your opinion (not the Court's)?

What are you arguing? That legislation should not be subject to a substantial affects test?

235 posted on 10/16/2005 10:35:37 AM PDT by Mojave
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To: Mojave; radioman

See #229. It's not everyday that one works all night to dig themselves out of a hole only to have their ace card turn out to be a joker that repudiates their entire credibility.


236 posted on 10/16/2005 10:36:52 AM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: Mojave

I don't understand what you gripe is about the quotation marks. Where I've quoted something, I think I've used the quotation marks. Where I have paraphrased, I have not. I'm not trying to do anything sneaky here.

Do you have anything of substance to add to this discussion or are you just here to pester and insult people?


237 posted on 10/16/2005 10:37:26 AM PDT by TKDietz
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To: Mojave

I don't understand what your gripe is about the quotation marks. Where I've quoted something, I think I've used the quotation marks. Where I have paraphrased, I have not. I'm not trying to do anything sneaky here.

Do you have anything of substance to add to this discussion or are you just here to pester and insult people?


238 posted on 10/16/2005 10:37:47 AM PDT by TKDietz
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To: Mojave

I don't understand what your gripe is about the quotation marks. Where I've quoted something, I think I've used the quotation marks. Where I have paraphrased, I have not. I'm not trying to do anything sneaky here.

Do you have anything of substance to add to this discussion or are you just here to pester and insult people?


239 posted on 10/16/2005 10:37:56 AM PDT by TKDietz
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To: TKDietz
I don't understand what you gripe is about the quotation marks.

Quit running. Who are they quoting?

240 posted on 10/16/2005 10:38:52 AM PDT by Mojave
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