Posted on 01/31/2022 3:47:25 AM PST by ransomnote
from Epoch Times interview upthread...
Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching
Lucy Kerr, Flavio A. Cadegiani , Fernando Baldi, Raysildo B. Lobo, Washington Luiz O. Assagra, Fernando Carlos Proença, Pierre Kory, Jennifer A. Hibberd, Juan J. Chamie-Quintero
Published: January 15, 2022 (see history)
DOI: 10.7759/cureus.21272
Cite this article as: Kerr L, Cadegiani F A, Baldi F, et al. (January 15, 2022) Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching. Cureus 14(1): e21272. doi:10.7759/cureus.21272
Abstract
Background: Ivermectin has demonstrated different mechanisms of action that potentially protect from both coronavirus disease 2019 (COVID-19) infection and COVID-19-related comorbidities. Based on the studies suggesting efficacy in prophylaxis combined with the known safety profile of ivermectin, a citywide prevention program using ivermectin for COVID-19 was implemented in Itajaí, a southern city in Brazil in the state of Santa Catarina. The objective of this study was to evaluate the impact of regular ivermectin use on subsequent COVID-19 infection and mortality rates.
Materials and methods: We analyzed data from a prospective, observational study of the citywide COVID-19 prevention with ivermectin program, which was conducted between July 2020 and December 2020 in Itajaí, Brazil. Study design, institutional review board approval, and analysis of registry data occurred after completion of the program. The program consisted of inviting the entire population of Itajaí to a medical visit to enroll in the program and to compile baseline, personal, demographic, and medical information. In the absence of contraindications, ivermectin was offered as an optional treatment to be taken for two consecutive days every 15 days at a dose of 0.2 mg/kg/day. In cases where a participating citizen of Itajaí became ill with COVID-19, they were recommended not to use ivermectin or any other medication in early outpatient treatment. Clinical outcomes of infection, hospitalization, and death were automatically reported and entered into the registry in real time. Study analysis consisted of comparing ivermectin users with non-users using cohorts of infected patients propensity score-matched by age, sex, and comorbidities. COVID-19 infection and mortality rates were analyzed with and without the use of propensity score matching (PSM).
Results: Of the 223,128 citizens of Itajaí considered for the study, a total of 159,561 subjects were included in the analysis: 113,845 (71.3%) regular ivermectin users and 45,716 (23.3%) non-users. Of these, 4,311 ivermectin users were infected, among which 4,197 were from the city of Itajaí (3.7% infection rate), and 3,034 non-users (from Itajaí) were infected (6.6% infection rate), with a 44% reduction in COVID-19 infection rate (risk ratio [RR], 0.56; 95% confidence interval (95% CI), 0.53-0.58; p < 0.0001). Using PSM, two cohorts of 3,034 subjects suffering from COVID-19 infection were compared. The regular use of ivermectin led to a 68% reduction in COVID-19 mortality (25 [0.8%] versus 79 [2.6%] among ivermectin non-users; RR, 0.32; 95% CI, 0.20-0.49; p < 0.0001). When adjusted for residual variables, reduction in mortality rate was 70% (RR, 0.30; 95% CI, 0.19-0.46; p < 0.0001). There was a 56% reduction in hospitalization rate (44 versus 99 hospitalizations among ivermectin users and non-users, respectively; RR, 0.44; 95% CI, 0.31-0.63; p < 0.0001). After adjustment for residual variables, reduction in hospitalization rate was 67% (RR, 0.33; 95% CI, 023-0.66; p < 0.0001).
Conclusion: In this large PSM study, regular use of ivermectin as a prophylactic agent was associated with significantly reduced COVID-19 infection, hospitalization, and mortality rates.
I think it’s more likely that the Founding Fathers of your great Republic put on paper what God bestowed to every human on earth. Canada was very late in putting those same God-given rights on paper, and expressed them slightly differently, but I believe the rights exist everywhere and can’t be taken away by governments, except by force.
Canadians have all of the rights Americans have because rights come from God. The Canadian government denies those rights to the people.
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Agreed. You said it first and more succinctly. Thank you.
https://t.me/s/TaskForce_PPTF
Task Force - PPTF
Forwarded from
🦅 Aquila 🦅
BIG BREAKING NEWS 🇺🇸⚡
The Pentagon Press Secretary stated that the majority of the 2,000 troops from Fort Bragg (82nd Airborne and 18th Airborne Corps) will be deployed to Poland 🇵🇱
#3594 - 11/13/19 #3895 - 3/21/20 Future World Music - Victory Of Life https://youtu.be/_MK0j765ko4
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Thank you, lj, for compiling the list so long ago and to numberonepal for posting it again today. I went to my favourite above and listened a few times while I read the uplifting comments from all over the world below it. I needed that reinforcement today as this horror movie drags on a bit too long for my temperament and everyone’s safety.
Re Zucker:
That’s pretty great!
Same.
Correct on the butt. 😬
Surreal, Americans lethargy shocked the world.
But for pockets here and there, the peeps did nothing for too long, have still lead in nothing, demanded nothing, but discussed patriotism and added butter to the popcorn, watched the Show wondering why Q is delayed. (Dumbest saying, ever.)
Hopefully, if bellies rumble and we run out of popcorn to eat, the sleeping giant will growl and arise.
If anything is the Keystone, We are. I know you think so.
One Person's Response to the FRee Republic thread post: The QAnon Phenomenon
2/2/2022 | vanity
Posted on 2/2/2022, 11:10:00 AM by ransomnote
It got pulled. :(
EVERY YEAR WILL BE OUR YEAR!!! pic.twitter.com/vXU9Is229i— il Donaldo Trumpo (@PapiTrumpo) February 2, 2022
The gloves are off. He’s not playing nice.
YESSSSS! I sent emails and letters to my local Member of Parliament urging just that and I’m gratified that he and others are/were listening. In my correspondence, I laid out how O’Toole was behaving as just another globalist and Trudeau lackey and concluded that it was impossible to tell him and Trudeau apart in their party platforms. Such great news. Let’s see who the power brokers try to foist on us now.
Started, can’t read it through. After a few sentences I think they’re gloating about how we were all fooled into following a false prophet. It’s meaningless drivel because lions don’t care about the opinions of sheep.
You’re an activist now though am sure a polite one not scrappy like your neighbours to the south.
I just read Emerald Robinson’s piece. Very condemning. Either Pence is a dupe or he is swampy. He reminds me of Gov. Abbott.
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