I’m not an MD but I can read, and everything I’ve read says HCQ does the most good when given as early in the progress of the disease as possible. And the reasons why make sense.
And yet today, there was a French Dr on with Dr Oz-whom I aint no fan of but wife is, that siad it works if taken at the right time.
Of those that died, he said that it was to late since they were already on ventilators.
>> Looking just at deaths, 2.8% of the patients who took hydroxychloroquine died, and 4.6% of the patients who did not take it died. That difference was also not found to be statistically significant. <<
So, you design a study with an impossibly small sample size, and when the HCQ cuts the death rate by 40%, you claim that the reduction is “statistically insignificant.”
“Looking just at deaths, 2.8% of the patients who took hydroxychloroquine died, and 4.6% of the patients who did not take it died. That difference was also not found to be statistically significant.”
So 1.6 fold more survived when taking the drug.
Drugs can approved on that.
Most conclusions would be a lager cohort is needed.
They do people on high dangerous doses that are known to cause these issues and act surprised, they should be flogged out of the profession
“No evidence of clinical efficacy of hydroxychloroquine in patients hospitalised for COVID-19 infection and requiring oxygen: results of a study using routinely collected data to emulate a target trial”
“We used data collected from routine care of all adults in 4 French hospitals with documented SARS-CoV-2 pneumonia and requiring oxygen >= 2 L/min”
https://www.medrxiv.org/content/10.1101/2020.04.10.20060699v1.full.pdf
this study was designed to fail: every medical professional who’s worth their salt KNOWS absolutely that most antivirals are basically only effective when given no later than 48 hours after symptoms appear ... a study constructed like this one would have concluded that ALL anti-influenza antivirals and all anti-shingle antivirals were ineffective ...
“This is Xi-NN” - all the “news” that Xi wants “reported”.
I took this drug for years as I worked in Nigeria. It was for prophylaxis of Malaria. I was not a medical professional then as I was just a geologist working in Nigeria. Malaria sucks.
Today I am a medical professional as a clinical pharmacist, and thankfully retired now. This drug does have side effects as most drugs This drug is used by millions of people in Africa and Asia. Its side effects are well known and rather minor. Malaria truly sucks big time. I had it do to my stupidity of not taking the drug. I was offshore many miles and did not consider a mosquito bite. I was wrong.
It was a hell of a diet. A few hours in bed with blankets over me and shivering. A few hours after on top of the blankets nude and sweating. The chills and shivers were the worst. After the fever one could sleep for a few hours and it then all started over again. This went on for a few days. I lost 10 pounds in 15 days. I do not recommend this diet.
When the chills and fever were over for a few hours I would go down to the mess hall on the drilling rig. I would ask for nothing except warm rice and butter. I was not hungry but knew I needed food. Oddly I continued to perform my job. I was young and bullet proof then. I am not such now
Malaria Sucks
1. Penirillin won’t work to cure someone who already has gangrene. This is a FALSE study - it was designed to fail, but giving a medication when the patients were already overwhelmed. The best use of HCQ is early in the course of coronavirus, and given in conjunction with azithromycin and zinc. If this study had done this, the results would have been different.
2. WRT side effects, particularly heart issues, AGAIN this study was designed to fail. First, HCQ only has bad effects after long-term use. Doctors treating patients with RA or Lupus do NOT test their patients’ hearts before prescribing HCQ for a reason - because there IS no reason to do so. Example #1, my 82 y.o. mother, who has RA and has been on HCQ every day for the last 5 years - DESPITE having a cardiac arrhythmia for the last 15 years has had ZERO side effects - not WRT her heart, nor retina problems (another possible LT problem with HCQ).
This is a safe medication. Those against using it for treating the coronavirus are, almost to a person, very much anti-Trump. They are literally hoping/advocating for people to die in order to make Trump look bad. Scumbags, all.
Ah, Dr. Offit. The vaccine industry’s chief propagandist. They’re all coming out of the woodwork now.
they are french, the study surrendered before it began.
those cheese eating surrender monkies.
and fu i’m part french so fu if you’re offended
So, dosing a person with final death rattles doesn’t rejuvenate them...I knew it was too good to be true.....I just knew it....
Clinical trials investigate when a drug is useful, when it’s not, proper dosage, and side-effects. All this information is good. Eventually, we will know what we have. It won’t be magic. It’ll be calibrated. In the meanwhile, we’r using the drug on a compassionate basis. For many, it’s not only the best hope, it’s the only hope. Yes, I. agree, better to prescribe hydroxy early. And, did I mention, it’s cheap.
When I see anything posted on here from CNN or the Washington Post I move on. No sense in reading anti-American and anti-Trump drivel.
So only go to Dr Offit if you want to die. He won’t even try to help you. He should be called Dr Death.
France: It worked until it didn’t
GIGO
Garbage In Garbage Out