There aren't many answers. Maryland and Jamestown are two such answers. I know from my own family history since they WERE exactly what I described. There's a reason why they came in 1649 specifically. That was the year James I was beheaded after the Roundheads won the English Civil War. If you were of any religious persuasion in England/Wales other than a Puritan (yes even other Protestant sects), it was time to get the hell out.
Same personal fantasy and ignoring all historical fact.
Catholics in British America
“There were only about 300 Catholics in Virginia at the time of the American Revolution.”
“in 1765, the Catholic minority in Maryland numbered about 20,000.”