Why not? They did it then, we can do it now. This moment is ripe for these kinds of discussions and gets to the heart of draining the swamp. Or at least speaks to it.
You would not want to be treated based on the medical science and ideas of 1787. Why would one attempt to address constitutional issues today in the terms in which they were discussed when the Constitution was drafted, debated, and ratified?
Indeed, Madison's Notes, the Federalist Papers, the Anti-Federalist Papers and other sources of that era are remarkable for the range of historical and contemporary knowledge they invoked. Federalist and Anti-Federalist alike of the founding era would be astonished if we ignored what had happened since then, especially our long history under the Constitution and the issues we face today.