If the F-16 has 3 external fuel tanks it would probably have enough fuel for the attack.
The A-50 may be the only radar system that could detect the F-16s in time to negate the attack.
I doubt the F-16 would be able to get within Aim-120 range of the A-50.
🇷🇺Russian Su-34 fighter-bomber WAS SHOT DOWN while launching X-59 missiles in Kherson region.
AIM-120D’s have range of 86-100 miles; is it possible that this missile was used?