Treating Covid-19: Everyone was wrong about ivermectin

Washington Examiner ^ | 11/18/2021 | Kaylee McGhee White,

[aynrandfreak]

Scott Alexander is a lefty psychiatrist who likes statistics, who admitted that being for Ivermectin would turn the Establshment against anyone, but yet he thinks he claims he was being objective on which studies he disregarded.

[mewzilla]

If you'd like to get your geek on, a fascinating link...

Effect of Ivermectin and Atorvastatin on Nuclear Localization of Importin Alpha and Drug Target Expression Profiling in Host Cells from Nasopharyngeal Swabs of SARS-CoV-2- Positive Patients

[FreedomPoster]

Both HCQ and Ivermectin have safety profiles at about the level of aspirin, and safer than Tylenol.

The demonization of these two drugs was criminal. I believe it caused much illness and death. And there was no reason for it, the drugs are safe as could be.

#CrimesAgainstHumanity

We need Nuremberg 2.0 to teach some people a lesson.

[Amendment10]

Thank you for referencing that article SeekAndFind. Please note that the following critique is directed at the article and not at you.

The referenced article “overlooked” that the patent on Ivermectin is long expired. In other words, and emphasizing that I don’t know anything about pharmaceutical industry, it is probably more profitable for Big Pharma to sell experimental “vaccines” that use non-expired patents to big government.

In fact, a freeper mentioned several hundred dollars per shot awhile back.

Also, it would be interesting if medical history would have turned out better if vitamin D3 had been discovered before vaccines were.

Insights welcome.

[TLI]

Thanks.

I was one of those normal people that started off cheering for the arrival of the vaxx but prepping for Quercetin / Zinc sulfate / Vit D, C, etc.

Then information starting popping up about the vaxx.

Followed all the stories and now I just want the ones that knew the vaxx was pathetic and HCQ/Zinc and Ivermectin really did work to pay for their crimes.

.

[sourcery]

I can't say that de-worming doesn't help against COVID-19, but it's scientifically IMPOSSIBLE that that's the only reason it helps:

• Oklahoma Doctors Have Tremendous Success in Treating Nursing Home COVID Patients with Ivermectin
• Do Antiviral Pills Negate The Need For Vaccine Mandates?

  Two of the major pharmaceutical companies are about to get approval to market "anti-viral" therapeutic pills that are more or less as effective as the vaccines they currently market. Those pills' method of action is based on the same anti-viral mechanism the Ivermectin drug uses.

• Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

  Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified.

• Effectiveness and Safety of Ivermectin in COVID‐19 Patients: A Prospective Study at A Safety‐Net Hospital [Ozer et al., Journal of Medical Virology, doi:10.1002/jmv.27469 (Peer Reviewed)]

  Small prospective PSM study in the USA, showing 75% lower mortality with ivermectin treatment, without reaching statistical significance, significantly shorter ventilation and ICU time, and longer hospitalization time.

  Authors leave the statistically significant improvements in ventilation and ICU time out of the abtract and conclusions, and incorrectly state that there were no differences in other outcomes (there were no statistically significant differences) [1]. Authors are ambiguous on the primary outcome, referring to the primary mortality outcome in one case, and "clinical outcomes, measured by the rate of intubation, length of hospital stay, and mechanical ventilation duration" in another case.

  The longer hospitalization time may be partially due to the greater mortality in the control group.

  risk of death, 75.0% lower, RR 0.25, p = 0.09, treatment 2 of 60 (3.3%), control 8 of 60 (13.3%), PSM.

• Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication [Low et al., Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, doi:10.1016/j.bbadis.2021.166294 (Review) (Peer Reviewed)]

  Review of the antiviral characteristics of ivermectin and mechanisms of action. Authors note that ivermectin has proven effective for HIV-1, Adenovirus, flu, SARS-CoV, and more; due to genomic similarity between SARS-CoV-2 and SARS-CoV, the role of the IMPα/β1 complex for viral protein (NSP12-RdRp) shuttling between the nucleus and cytoplasm holds great potential; and that ivermectin exhibits great potential in reducing SARS-CoV-2 viral replication via numerous modes of action, such as the disruption of the Importin heterodimer complex (IMPα/β1).

  

• Favipiravir and Ivermectin Showed in Vitro Synergistic Antiviral Activity against SARS-CoV-2 [Jitaboam et al., Research Square, doi:10.21203/rs.3.rs-941811/v1 (Peer Reviewed) (In Vitro)]

  In Vitro study showing a strong synergistic effect of ivermectin and favipiravir. Combining multiple antiviral drugs with different mechanisms of action helps to minimize drug resistance and toxicity.

Bottom line: To claim that a therapeutic drug with known, proven antiviral action against virii in general, and against SARS-Cov-2 in particular, is only effective because it kills worms is an extraordinary claim, and so requires extraordinary proof.

[chopperk]

https://www.youtube.com/watch?v=I03JFB3LoF4

[JPG]

If I recall “The Donald” mentioned ivermectin early as well as Hydroxychloriquine. ...

Wonder where we'd be today if had said DO NOT use them under any circumstances.

[consult]

Thanks for posting! This analysis is very detailed and explains why so many have been fooled by ivermectin.

https://astralcodexten.substack.com/p/ivermectin-much-more-than-you-wanted
The Summary

Ivermectin doesn’t reduce mortality in COVID a significant amount (let’s say d > 0.3) in the absence of comorbid parasites: 85-90% confidence

Parasitic worms are a significant confounder in some ivermectin studies, such that they made them get a positive result even when honest and methodologically sound: 50% confidence

Fraud and data processing errors are of similar magnitude to p-hacking and methodological problems in explaining bad studies (95% confidence interval for fraud: between >1% and 5% as important as methodological problems; 95% confidence interval for data processing errors: between 5% and 100% as important)

Probably “Trust Science” is not the right way to reach proponents of pseudoscientific medicine: ???% confidence

[CtBigPat]

“They” were not wrong, they intentionally LIED to us for the profit of Big Pharma.

[babygene]

Viruses are small obligate intracellular parasites, which by definition contain either a RNA or DNA genome surrounded by a protective, virus-coded protein coat.

Google it...

[BeauBo]

“Ivermectin acts as a protease inhibitor... The interesting thing is the soon to be given EUA pill that Pfizer developed to treat Covid is also a protease inhibitor according to their research.”

Some are jokingly calling Pfizer’s knock off “Pfizermectin”.

[TigersEye]

Ivermectin, ‘Wonder drug’ from Japan: the human use perspective Feb. 10, 2011 - ncbi.nlm.nih.gov

Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin—originating solely from a single microorganism isolated at the Kitasato Intitute, Tokyo, Japan from Japanese soil—has had an immeasurably beneficial impact in improving the lives and welfare of billions of people throughout the world.

(snip)

There are few drugs that can seriously lay claim to the title of ‘Wonder drug’, penicillin and aspirin being two that have perhaps had greatest beneficial impact on the health and wellbeing of Mankind. But ivermectin can also be considered alongside those worthy contenders, based on its versatility, safety and the beneficial impact that it has had, and continues to have, worldwide—especially on hundreds of millions of the world’s poorest people.

[mass55th]

"We need Nuremberg 2.0 to teach some people a lesson."

I'm with you on that, and it needs to be more thorough, and more encompassing, with more punishment being doled out than the original Nuremberg did.

[GBA]

Parasites suppress the immune system, making it more difficult for the human body to fight off viruses. Thus, getting rid of worm infections makes it easier for COVID-19 patients to bounce back from the virus.

So they’re saying covid patients have worms?

And the reason ivermectin works is due to it removing the worms?

But .. are the worms the reason why they have covid?

Did they get covid from the worms or because they have worms?

If you don’t have worms, are you immune to covid?

[drSteve78]

If ivermectin was acknowledged as a treatment, even marginally, then the Emergency Use Authorization for the Covid jabs would disappear. Simple. As. That.

[drSteve78]

Further, FYI, one of the drugs to treat AIDS as an immune system stimulator is Levamisole. There was a time when gay men were having difficulty paying for the $1200 per dose therapy, and suddenly there was a shortage of sheep/goat deworming boluses.

Yes friends, gay man were taking sheep dewormer. At $8 per bolus, cut in four pieces.

[devere]

Mr. Alexander’s idea is idiotic.

The biochemistry of how Ivermectin stops the virus is well understood.

This smells like last gasp misinformation by the NIH/FDA/CDC mafia.

[Cobra64]

Here is the No BS (video) history of the development and prescriptions of Ivermectin.

https://rumble.com/vlpecw-the-story-of-ivermectin.html

[Cobra64]

HCQ was developed for malaria. It’s been repurposed for Covid. Early on, Trump pushed and took HCQ. Remember?