I really don’t know much about this all works.
Is it companies with more than 100 employees.
A family member escaped the shot where he works. because while the company has a hundred employees his specific department only has about a dozen.
Government-by-decree is how it works. There are no laws or even a definitive executive order to make this legitimate. Only a "policy statement" from an anonymous Federal bureaucrat is needed.
Most Religious exemptions will be denied.
Most Medical exemptions will be denied.
The few exemptions granted will be temporary and conditional on onerous and expensive testing requirements. Companies have already announced large health insurance surcharges that will be imposed on staff who are not vaccinated, or whose other family members are not vaccinated.
The Courts have been of no help in this matter. They will continue to do nothing.
Is it companies with more than 100 employees>.
At this moment, it is all companies with more than 100 employees - and all companies, regardless of size, doing business with the Federal Government through the GSA bidding process.
I have small business clients who have been directly affected. They will comply ("all staff must be vaccinated") or they will be forced to shut down. They are all going to comply.
I know of some large businesses that have backed away from the mandates. This is a temporary retreat due to critical staff shortages. The "mandates" will be applied for all new hires. They will come back later for existing staff members.
All of this is subject to change at the whims of the Federal bureaucracy. That is how it works.