Posted on 09/09/2021 6:58:17 AM PDT by numberonepal
Niacin and Melatonin work in synergy. The melatonin opens the gateway to cells and the inflammation within the cells. Niacin gets inside and kicks the crap out of it. We are all depleted of melatonin, so everyone's doses are different.
The Sweet Spot is when there is No Flush. Not even a tingle occurs. Hence, all the melatonin is being used up as well as the niacin to remove inflammation and restore the cells to homeostasis. The Flush is when excess niacin is not being used by the melatonin and goes to the skin capillaries.
The environmental stresses of modern life can lead to shortages of nutrients, especially melatonin and niacin, leading to the accumulation of free radicals and inflammation. The virus was targeted to affect the ACE2 receptors, which are regulated by melatonin and niacin. Once in your cells the virus consumes your energy, depletes melatonin, down-regulates the ACE2 receptors (especially in the intestines producing a leaky gut) giving the virus and spikes easy access to your brain and nervous system through the Vagus nerve.
The virus thrives in a melatonin/niacin deficient environment. The virus uses the energy from inflammation for its fitness (fuel). Supplementing melatonin and niacin reduces the inflammation that makes your body more vulnerable and reactivates your immune system to take care of the virus.
Over the course of life the lack of nutrients, especially melatonin and niacin, can't counter the progression of bad health behaviors throughout that life. New exposures like electronics, geothermal shifts, etc, a stressful life and poorer quality food these days all compound these deficiencies. Our continued dynamic deficiency in especially NIATONIN (niacin/melatonin) leads to the accumulation of more energy not expended out as per in. Because of this free radical electrons form and inflammation accumulates.
It's literally like the virus and covid pathogenesis, just slower.
These viruses or their gain of function research - whatever you want to imagine it is - have evolved since SARS-1 in 2000 to target these energy receptors; aka ACE2; what niacin and melatonin regulate.
It's a feasting ground for them (viruses).
Note:
Niacin and melatonin regulate ACE2 (Angiotensin-converting enzyme 2).
ACE2 is an enzyme attached to the membrane of cells located in the intestines, kidney, testis, gallbladder, and heart. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin.
They're (viruses) thermodynamically attracted to people who have more inflammation for them to use for their fitness (fuel). These high expressed ACE2 (aka niacin receptors) along with the SR-B1 coreceptor right next to it - they (virus) sneak in this.
Note:
SR-B1 is a scavenger receptor class B type 1. It functions as a receptor for high-density lipoprotein. It is also know as CD36, a scavenger receptor class B member 3.
SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport
https://pubmed.ncbi.nlm.nih.gov/25211142/
The SR-B1 is where HDL dumps off cholesterol from blood into tissue to prevent atherosclerosis. Because the cholesterol was leaking out of the tissue after it reached threshold, it can not contain it anymore due to too much pressure. As a result, HDL lowers because it's not getting developed in the liver anymore. The HDL has to attend to scooping more cholesterol back into tissue, and is used up real quick.
The virus then gets in cells and as it literally continues to consume your energy until it reaches a threshold it needs of energy to double (replicate). As it does this it depletes melatonin. It also makes it a lot easier if you have deficient melatonin. You can see now why unhealthy and older people who have not had enough melatonin and niacin as most at risk. They also have low HDL/high TG (triglycerides). The depleted melatonin makes the PDC receptor, already stunted from accumulated inflammation over a lifetime, from pyruvate to Acetyl-CoA even more stunted. Due to this melatonin gets gradually even more depleted into say long haul COVID. As soon as the virus meets threshold to replicate it moves out the mitochondria, and on to the next one (cell) like a bad ex-girlfriend. Repeat forward. This is why COVID long haulers flush like crazy with even 50 mg doses of niacin.
Note:
• Type I interferons (IFNs) derived from plasmacytoid dendritic cells (PDCs) are critical for antiviral responses
• Pyruvic acid or pyruvate is a key intermediate in the glycolytic and pyruvate dehydrogenase pathways, which are involved in biological energy production.
• Acetyl-CoA is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.
As the virus leaves each cell, it and all the crazy inflammation it amplified [hypered], leaves melatonin depleted and stunts further the PDC from pyruvate to acetylCoA. This is needed for AAANAT receptor from tryptophan to serotonin to melatonin stunted too, and so melatonin isn't made more and more.
Note:
The key regulatory step in melatonin synthesis is catalyzed by arylalkylamine N-acetyltransferase (AANAT), which converts serotonin to N-acetylserotonin.
This leaves ACE2 downregulated, and happens especially in the intestines/colon.
This is how the virus/spikes - like IVM gains easy access to your brain/nervous system then - your gut becomes leaky with this ravaging of melatonin and inflammation. This gives easy access through the Vagus nerve to cross into BBB (blood brain barrier) and nervous systems where the most bang for the buck energy is for them.
Basically the virus/spikes have to deplete your already deficient melatonin and niacin to succeed and be thermodynamically attracted in the first place.
So keeping NIATONIN sufficient/repleting it takes back control of YOUR energy metabolism that the spikes try to take over for their food (energy).
It (NIATONIN) doesn't just push out inflammation. It allows T-cell differentiation (melatonin through ACE2 aka GPR109A expression). Then niacin comes in which is literally an innate/mandatory function of the recruitment and facilitation of T-cells, killer cells, and B cells. It induces phagocytosis, denatures, kills, and clears the virus as well as all pathogens and all toxins. It's a feasting grounds for them.
Note:
GPR109A (encoded by Niacr1) is a receptor for butyrate in the colon. GPR109A is also a receptor for niacin, which is also produced by gut microbiota and suppresses intestinal inflammation.
https://pubmed.ncbi.nlm.nih.gov/24412617/
NIACIN: https://purebulk.com/products/niacin-vitamin-b3-immediate-release?sca_ref=1004090.8JspdBHd04…
MELATONIN: https://purebulk.com/products/melatonin?sca_ref=1004090.8JspdBHd04…
Precision (0.000 g) Scale: https://purebulk.com/products/gemini-20-digital-scale?sca_ref=1004090.8JspdBHd04…
This graphic contains the protocol. Please read it all, especially the top portion where is says to eliminate certain things while using the protocol.
The latest addition to the protocol is L-leucine — and it’s a biggie. Since early on in the niatonin experiments, I had some skin issues, first with a plague of blackheads down the middle of my chest and then with a rash on my ankle.
After two days with leucine, both of these improved noticeably, and I’m hopeful that they will be resolved entirely.
Thanks for the update. I haven’t checked in for a minute. What’s it even called now?
Interesting correlation:
Anti-leucine rich glioma inactivated 1 (LGI1) autoimmune encephalitis (AE) following #CovidVaccination (Pfizer-BioNTech, 2nd dose):
https://frontiersin.org/articles/10.3389/fimmu.2021.813487/full
- Case of a 48-year-old man
⇒ Rapidly progressive cognitive decline & hyponatremia
It’s now called Hom3ostasis.
Dmitry now has a membership web site: http://hom3ostasis.com
The pertinent Telegram channels are:
http://t.me/hom3ostasistestimonials
and
Lucky me — I have tested positive for COVID. I spent last week at convention in Salt Lake City, and came home to a report that one of my colleagues had tested positive. I was feeling a little run down and had a little cough, so I tried out my free government test kit. The first test was inconclusive, but the second test was definitely positive.
I reported my situation on the Hom3ostasis Telegram channel. Within minutes, Dmitry offered some suggestions: increase my niacin, replace leucine with arginine (the latest addition to the protocol), add beef liver, and decrease lipoic acid. I ordered the arginine and implemented the other changes.
“at convention” -> “at a convention”
... actually the annual convention for Young Living essential oils.
I was feeling a little run down and had a little cough, so I tried out my free government test kit.
Hope it passes with little or no consequence, AZL!
It couldn’t hurt to do a little MMS protocol.
Are you getting any sun?
I followed Dmitry’s advice and slammed the coof with extra niacin. I also threw in some NAC and started L-arginine today. I think the coof has surrendered. My little cough is almost gone and I have more energy.
I went out for a walk this morning in the neighborhood just north of me — and encountered a real-life crime scene investigation. There were eight vehicles including a “crime scene unit”, a pickup from the local fire department, a couple of marked police vehicles from the Marana PD, an SUV from Pima County, and two black suburbans. I saw them take a gurney from the Pima County vehicle into the house, but I was distracted when they took it back out.
Later, when I asked an LEO what was going on, he said it was just a “medical issue”, not a real crime scene.
Right.
But at least I got some sun.
MMS?
My bout with the coof is over now, including 99% of the (minor) cough. I am now among the naturally immune.
Sadly, I do have one remaining issue. I realized over the past couple days that I have lost my sense of smell. Any skepticism I might have had about the result of the free government test was allayed by the fact that I now have what I saw as the definitive symptom. This now means that my poop smells like rose petals and also like a lump of granite, i.e, NOTHING.
I can still taste things, but smell is kaput.
I seem to recall that zinc would help recover the sense of smell, so I’m trying that.
Too much zinc can also diminish sense of smell. There have been studies that say if you challenge your sense of smell- daily regular smelling of essential oils and peanut butter coffee lemons etc can help recover it
Thanks. My brother used a similar approach to recovering smell after radiotherapy. I’ll give it a shot. With a couple of hundred essential oils in my inventory, I can start there.
🙏
I got my sense of smell back. When I mentioned the problem to a Costa Rican friend, she recommended something called Potenciator. I think it’s for IV use, which I wasn’t going to do. But I looked up the ingredients and found that the main active ingredient was L-arginine, an amino acid that had just been added to the niacin protocol a couple of weeks before. I had already purchased some, but hadn’t begun to use it yet.
After five days (as my friend predicted) with five grams of L-arginine twice a day, along with the niacin of course, my sense of smell was as good as new. L-arginine tastes terrible as a powder mixed into water — but it was worth it.
L-arginine was only in the protocol briefly, like many other candidate ingredients. It has now been supplanted by creatine (not to be confused with creatinine).
Last I checked (a week or so ago), the basic protocol is now down to three ingredients: niacin, creatine, and lipoic acid. There must be a dozen or more other ingredients which can be added “as needed” or “to comfort”.
How friggin AWESOME is that??? Very happy for you. Thank you VERY much for sharing!! God bless!
Hey, I just noticed Dmitry’s Telegram channel is no more. I haven’t gotten on to look in quite a while, but used to occasionally look up various topics there by keywords, to glean certain specific info and insights.
Are you a member of his private group? If so, I wonder if he’s ever given any specific advice on dealing with bad aftereffects to the kidneys from being given Remdesivir. This happened to someone I know, and I’m trying to search for helpful info. He still has lingering impaired lung function from the coof/pneumonia as well, and is unjabbed. Thanks in advance for anything you might be able to find out!
The Telegram channel is still there as https://t.me/HOM3OSTASIS.
I searched there and found nothing for Remdesivir recovery. I would try the niacin protocol as is, since it seems to be good for just about everything, especially including long-haul COVID.
I am a member of his private group, but most of the Q&A still goes on through Telegram. If you get a premium subscription, you can ask Dmitry questions in live sessions.
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