Red states will resist.
I agree with that, unlike 1994, there will be state-level resistance in a handful of places, South Dakota or Texas maybe, for example. But you won’t be “safe” if you happen to live in one of those states, and most of it will be bluster. Federal law enforcement will operate with impunity, local and state state law enforcement may not assist, but they won’t prevent either. If a state resident of some resistant state is arrested the governor will bluster and demand that “something be done!” And then it’ll drop out of the news.