Sure looks like firing from the lower floor there.
What appears to be muzzle flashes are very distinct, and it is not a reflection, because it is only from that window.
https://twitter.com/joebennett4321/status/915066349126393856
Check at 4:57 in the video—video from car passing Mandalay Bay picks up rapid flashing from a 4th(or so) floor window.
I noticed this Tweeter sent this to Sean Hannity also.
Thanks Cowgirl of Justice.
All the smoke from the shooting set the Hotel fire system off, which includes flashing strobes. I've read elsewhere the flashes in this video are from these strobes.
Was the window busted out?
Strobe light, not muzzle flashes, check my post above.