True driverless cars and especially large trucks will have to have centralized control and tracking systems. Which means they’ll be vulnerable to hacking and the fun will begin. The hackers and thieves and hijackers will be hard at work developing ways to defeat the systems and usher in a new form of auto thievery and general theft.
As for new crimes, absolutely. Every new technology has brought about new crimes and new crime control strategies.
Depends on one's definition of centralized control. There will be centralized control of where the vehicles go and when and that will especially apply to fleets of Uber type, taxi vehicles and over the road tractor trailer rigs.
And there will certainly be changes of plans at times and many vehicles will be reprogrammed from a central location.
Lots of centralized control on fleets of vehicles, but not so much on individually owned vehicles.