Once AIs are capable of self reproduction (completely, from raw materials), we become redundant. They would be able to program themselves without any code to protect their “makers”.
I don't know that this would be any solution. A cyborg would no longer be human. He/she/it would be superhuman and might view the rest of us as puny irritants.
But even if that kinda sorta worked out, there would always be someone or some group developing a standalone AI that would have no human-centric ethical qualms.