Good question. I would guess that he will/would handle with some simple gracious response such as ‘ I accept the participation of all who would make the US the nation intended by the Founders. I am not driven by any other notion’.
There seem to be indications that she is pro-abortion and pro-gay marriage, as on her Wiki page and a some other whack-media vehicles, though I’m trying to nail these down specifically.
That could be pretty thorny for Cruz.