I know your pain. I had to get both shoulders rebuilt when I was 40 yrs old and couldn't lift my arms to shut off the alarm clock. It was more due to my clavicle scraping my humerus joint, but the surgeon commented on "the extremely active life" I've led. In years past, @ 168 lbs, I was matching Nate Newton, the all-pro, 350lb lineman for the Cowboys, rep-for-rep on the lat pull down (probably 375lbs x 5 reps). Yeah, it kind of hurt my spine too.
Trying to get my joints back up to par, I've been doing 3 days light weight/high rep and 3 on cardio. No supplementation, although I've upped my water intake a bit to help keep the system flushed.
I hate to admit this, but I've been thinking of getting in to crossfit. Most lifters frown on it as it leans you out a lot and the granola-munchers have kind of infiltrated it. But, that's kinda what I'm looking for now. Leaner, less bulky.
Getting too old to be carrying this much weight, even in muscle much less fat.