Mrs BN & I both have been using laptops in lieu or desktops for several years.
No problems at all.
Mrs has a Netbook and I bought her a separate LCD monitor at Goodwill for $25, but she seldom uses it.
We have a wireless printer, so we usually work in the living room or dining room and can print in the office if need be.
Yep. I’ve gone with an Asus Eee PC netbook as my regular computer. Very handy, can take anywhere, also much more rugged than a regular laptop.
I’ve narrow fingers so don’t mind the slightly reduced keyboard. Still once in a while I come across a web site that doesn’t scale quite right with a popup, but the advantages outweigh that inconvenience for me.