That song used to be my lifesong. I related to it quite well. Without God, Life is short, meaningless, leads nowhere, amounts to futility, and ends in total oblivion, which is nothing more than black nothingness forever.
It's just an update to sentiments that have been expressed by humanity since long before Darwin came on the scene.
I met a traveller from an antique land,
Who said--"Two vast and trunkless legs of stone
Stand in the desert . . . . Near them, on the sand,
Half sunk a shattered visage lies, whose frown,
And wrinkled lip, and sneer of cold command,
Tell that its sculptor well those passions read
Which yet survive, stamped on these lifeless things,
The hand that mocked them, the heart that fed;
And on the pedestal, these words appear:
My name is Ozymandius, King of Kings,
Look on my Works, ye Mighty, and despair!
Nothing beside remains. Round the decay
Of that colossal Wreck, boundless and bare
The lone and level sands stretch far away."
Yes, of course. There have always been people who did not know God, and the hearts of those people despaired to find some meaning or purpose or hope in life. But, alas, without God, there is none. Neitszche certainly saw life for it truly is when it is denuded of the eternal and universals, and he despaired! The fact is that all humans beings have a yearning for fulfillment and wonder. Little children have a sense of wonder, but once they grow up (if they ponder life at all) that sense of wonder disappears and is replaced by loneliness, emptiness, longing for fulfillment. Many people without God seek that fulfillment in money, sex, drugs, alcohol, adrenalin, food, etc., but for a human being, enough of anything is never enough, becuase outside material stimulus cannot fulfill that inner yearning for fulfillment. God is the only one who can.