And I'll answer your question while I'm at it.
As phrased the answer to your question is yes, growing your own pot affects interstate commerce. Your question leaves out "intent". One could grow their own pot for resale, which is exactly what some do.
Growing pot for personal consumption IMO doesn't affect interstate commerce. Your opinion and mine may differ though.
How about this? If you built your own garbage disposal for you to use, would that affect the interstate commerce of garbage disposals?