It is not a problem for Creationists who believe that there is a reality beyond this physical universe.
Such a belief raises more questions than it answers as attempts are made to describe such a "reality" without reference to time or space. We are asked not only to accept something unobservable and incomprehensible, as space and time are inherent in all of our ideas. Then we are to suppose that the makings of things as complex as consciousness, sensory preception, and actuation are contained in this incomprehensible "reality". In short, we must simply accept what does not make any sense.
So the pursuit to explain the universe does not end because it is explained, but because it becomes inexplicable.
Here is your reference to time and space:
The universe is expanding at nearly the speed of light.
It cannot expand into nothing since there would be nothing into which it could expand.
Therefore it is expanding into something.
That "something" is outside of the universe.
Therefore there exists something outside of the universe.
If a postulate is invalid because it raises more questions than it answers, then truly evolution is invalid.