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To: lonestar67; All
AFAIK the chimp is the only other primate to be sequenced. Anybody know of others?

I said there is a 99+% identity in the coding regions between chimps and humans and 98% identity overall. Yes there are some areas where the differences are greater, especially in non-coding regions.

Don't go to a Creationist website to get your information, go read the Proceedings of the National Academy of Science article for yourself. Can't find the reference right now, but I'll be glad to look if you promise to actually read it. If you're not going to make the effort, then neither will I.

1,509 posted on 12/20/2005 6:46:12 PM PST by furball4paws (The new elixir of life - dehydrated toad urine.)
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To: furball4paws

I don't understand the problem here. I posted a link that was pretty clear. Here it is again:

http://www.wired.com/news/medtech/0,1286,57892,00.html

What is wrong with this?

Here is the conclusion of the article:


The Perlegen researchers compared human chromosome 21 with chimpanzee, orangutan, rhesus macaque and woolly monkey DNA sequences. In all the species, they found that DNA had been rearranged much more frequently during primate genome evolution than previously thought.

The DNA was often reordered in areas of the genome that contained functioning genes -- genes that researchers can investigate to find important clues about human health and the nature of disease.

The study didn't generate a new number expressing how similar or different chimpanzee DNA is from human DNA. However, researchers say, that number might be different depending on how it is measured anyway.

With new technologies like Perlegen's biochip, researchers can measure the genome at a much more minute scale than had been possible before.

The 98.5 percent difference between humans and nonhuman primates is based on differences between the two genomes' sequences of the letters A, T, C and G, which stand for the nucleotides adenine, cytosine, thymine and guanine. When researchers sequence the DNA of a genome, they use a machine like Applied Biosystems' ABI Prism 3700 to determine the order of the nucleotides. The letters form base pairs (A always binds to T and C always binds to G) that link together to form the rungs on the ladder of the DNA double helix.

But with technologies like Perlegen's "high-density array" -- a chip that allows scientists to look at whole genomes -- researchers can not only see missing base pairs, but also rearrangements of the base pairs in the genomes.

"(The research shows) how very interesting it is to look at small differences, whereas previously the focus was looking at broad differences," Gibbs said. "That's a suggestion of a paradigm shift."


1,513 posted on 12/20/2005 6:53:40 PM PST by lonestar67
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