You can pick your nose but you cannot pick your relatives especially your ancestors.. Some gene pools have been pee'ed in.. possibly ALL gene pools have been pee'ed in..
Why don't you just ping heartwood and ask her whether she or her parents or grandparents engaged in "long term inbreeding and incest... or chronic drug abuse including alcohol"?
Since sins only affect us unto the third or fourth generation, it shouldn't be hard to track down.