[b_sharp]

Recent examples of protein design in our laboratory include spontaneous self-assembly of a 15-residue peptide into a 45-residue parallel three-helix bundle metalloprotein, design of a 64-residue four-helix bundle ruthenium (II) metalloprotein, and construction of the first de novo designed heterobimetallic RuII.CuII three-helix bundle protein.

We have recently designed one self replicating system based on the leucine zipper motif of GCN4. One 32-residue alpha-helical peptide serves as a template to organize two constituent fragments in the proper orientation prior to ligation. Condensation of the two fragments produces a second template which can serve as a template for another such reaction

From here

[AndrewC]

Yeah?

The first paragraph seems to be a so what? And the second seems to cite the experiment I describe. That experiment "coaxes" one bond to form. Quite a self-replicating feat!(har)